Gamma-glutamyl transferase is primarily associated with which organ?

Gamma-glutamyl transferase (GGT) is an enzyme that plays a significant role in the metabolism of glutathione and the transfer of amino acids across cellular membranes. It is primarily found in the liver, making it a key marker for liver function assessment. Elevated levels of GGT in the blood can indicate liver diseases, such as hepatitis, cirrhosis, or liver tumors, as well as biliary obstruction and alcoholic liver disease.

While GGT can be found in smaller amounts in other organs, its highest concentration is in the liver, which makes it an important enzyme for diagnosing and monitoring liver health. In clinical practice, GGT is often measured in conjunction with other liver enzymes to provide a comprehensive evaluation of liver function.