Which of the following factors can lead to hemolysis in a blood sample?

Improper collection techniques are a well-known factor that can lead to hemolysis in a blood sample. Hemolysis refers to the rupture of red blood cells, which can release hemoglobin and other intracellular components into the plasma, affecting the sample's integrity and analyte results.

During the blood collection process, several factors may introduce mechanical stress or contamination. For instance, using a small-gauge needle can cause shear stress on the red blood cells, or vigorously shaking the collection tube after drawing can also lead to mechanical hemolysis. Additionally, not following proper protocols, such as allowing the alcohol used for skin disinfecting to dry completely before puncturing the skin, can also affect the sample quality.

Understanding the importance of proper collection techniques is crucial for ensuring accurate laboratory results. This helps in minimizing the risk of hemolysis and allows for reliable interpretation of tests conducted on the sample. Recognizing the impact of collection methods is fundamental for medical technologists to maintain quality control in laboratory practices.